Analytical Lab

Green Lab Best Practices Database Specialty Labs
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12 Principles of Green Analytical Chemistry

  1. Direct analytical techniques should be applied to avoid sample treatment.
  2. Minimal sample size and minimal number of samples are goals.
  3. In situ measurements should be performed.
  4. Integration of analytical processes and operations saves energy and reduces the use of reagents.
  5. Automated and miniaturized methods should be selected.
  6. Derivatization should be avoided.
  7. Generation of a large volume of analytical waste should be avoided and proper management of analytical waste should be provided.
  8. Multi-analyte or multi-parameter methods are preferred versus methods using one analyte at a time.
  9. The use of energy should be minimized.
  10. Reagents obtained from renewable source should be preferred.
  11. Toxic reagents should be eliminated or replaced.
  12. The safety of the operator should be increased.

Chromatography

  • Replace or reduce using toxic solvents, regents, preservatives, and pH adjustment additives

  • Minimize your sample size
    For example use microextraction techniques like Solid Phase Microextraction, Liquid Phase Microextraction, Nano-LC or capillary electrophoresis for DNA-/RNA-electrophoresis.

  • Minimize the number of samples
    Make the most of every experiment and try to get the most information possible out
    For example, use 2D-chromatography if you are working with complex samples (e.g. environmental analytics, etc.).

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